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SmartSign 24 Over item handling x 18 inch Oakland Mall “Slow Down 5 Sig Metal MPH” Limit Speed -

SmartSign 24 x 18 inch “Slow Down - Speed Limit 5 MPH” Metal Sig

$31

SmartSign 24 x 18 inch “Slow Down - Speed Limit 5 MPH” Metal Sig

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Product description

Color:18" x 24" 3M EG Reflective Aluminum

Reflective Signs Are Hard to Ignore
Our Slow Down 5 MPH Aluminum Signs have a reflective surface for extra visibility in dark and dim light conditions. Reflective surface means light thrown from headlights or flashlights will reflect back making the sign more readable.

3M Engineer Grade ["EG"] Reflective
3M Engineer Grade reflective signs are the most common material found on our public roads. 3M Engineer Grade signs have upto 7-year outdoor warranty.

USA's Oldest Sign Manufacturer
Family owned since 1918, we take immense pride in our signage. Being one of the oldest certainly means we know this business in and out. Our South Dakota factory is the oldest manufacturer of metal signs in the USA. We have been an integral part of safety and convenience our signs have provided over the years.

Industry Leading Durability
3M Engineer Grade signs have a 7-year outdoor warranty, but most signs last much longer. Our 80 mil thick signs are laminated for enhanced performance. You can clean off graffiti and your graphics are protected. Unlike many other signs, our Slow Down - Speed Limit 5 MPH signs use industry-leading 3M inks and not off-brand or other low-durability inkjet pigments that fade in a year or two.

SmartSign 24 x 18 inch “Slow Down - Speed Limit 5 MPH” Metal Sig

CURRENT ISSUE
November, 2021

No. 106 (11)

2020 Impact Factor: 9.941 Submission > Acceptance: 52 days
ARTICLES IN THREE SENTENCES
Article

Transducin β-like protein 1 controls multiple oncogenic networks in diffuse large B-cell lymphoma

Transducin β-like protein 1 (TBL1) plays a crucial role in controlling the stability of regulatory proteins involved in cell proliferation and autophagy induction. This study revealed that, unlike normal B cells, diffuse large B-cell lymphoma cells express abundant levels of TBL1 and its overexpression correlates with poor clinical outcome. Targeting TBL1 promoted lymphoma cell death in vitro and in vivo. These results provide the rationale for targeting TBL1 as a novel therapeutic strategy in diffuse large B-cell lymphoma.

Youssef Youssef et al.

Article

Targeting shear gradient activated von Willebrand factor by the novel single-chain antibody A1 reduces occlusive thrombus formation in vitro

The authors of this study developed a single-chain antibody that targets a shear gradient-specific conformation of von Willebrnad factor (VWF). In vitro studies showed that this antibody specifically reduces VWF-GPIbα binding and thrombus formation at sites of shear rate gradients but does not block platelet deposition and aggregation under constant shear rate. This characteristic places the antibody in a new class of antiplatelet therapy for selective blockade of pathological thrombus formation while maintaining normal hemostasis.

Thomas Hoefer et al.

Case Report

Massive cerebral venous thrombosis due to vaccine-induced immune thrombotic thrombocytopenia

A 26-year-old female developed vaccine-induced immune thrombotic thrombocytopenia (VITT) with cerebral venous thrombosis and bi-hemispheric hemorrhage following the first dose of the ChAdOx1 nCoV-19 vaccine. The treatment protocol, based on intravenous immunoglobulins, dexamethasone and argatroban was successful with almost complete clinical, laboratory and radiological response. This experience supports the application of an early and multidisciplinary therapeutic approach in cases of VITT, with the possibility of avoiding deaths and obtain a resolution of the syndrome.

Sara Bonato et al.

Letter

Allogeneic hematopoietic stem cell transplantation from non-sibling 10/10 HLA-matched related donors: a single-center experience

This retrospective study compared the outcome of allogeneic hematopoietic stem cell transplantation (HSCT) in 23 patients with hematologic malignancies transplanted from non-sibling fully matched related donors to that of patients who underwent conventional haplo-HSCT. Subjects transplanted from fully matched related donors showed trends to a higher relapse rate and lower cumulative incidence of grade II-IV acute graft-versus-host disease, but overall survival was similar. The authors concluded that individualized adjustment of the immunosuppressive treatment is reasonable for this category of patients.

Yaoyao Shen et al.

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